Though failure to replicate presents a serious problem, even highly-replicable results may be consistently and dramatically misinterpreted if dependent measures are not carefully chosen. This sentence comes from a new paper by Caren Rotello, Evan Heit, and Chad Dubé to be published in Psychonomic Bulletin & Review. Replication hurts in such cases because it reinforces artifactual results. Rotello and colleagues marshal support for this claim from four disparate domains: eyewitness memory, deductive reasoning, social psychology, and studies of child welfare. In each of these domains researchers make the same mistake by using the same wrong dependent measure. Common across these domains is that subjects have to make detection judgments: was something present or was it not present? For example, subjects in eyewitness memory experiments decide whether or not the suspect is in a lineup. There are four possibilities. ...